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What is VigRX Plus?

What is VigRX Plus?
We’ve covered you if you’re still unsure what VigRX Plus is. VigRX Plus is one of the most beneficial and popular male enhancement pills designed to boost sexual health naturally and more effectively.To get more news about vigrx plus pills, you can visit vigrxplus-original.com official website.

For over a decade, VigRX Plus has been a popular product and considered a game changer in the sexual lives of thousands of men. The product offers improved arousal, increases your sexual stamina, helps maintain sexual health, and enhances your overall intimate experience.

Since 2004, the product has been on the market. According to the manufacturers of VigRX Plus, the product helps increase sex drive. It is extremely useful for those with problems maintaining harder erections, penetrating their partner, and reaching an orgasm. As mentioned above, sometimes you experience really quick results, but sometimes you have to use it consistently and see results after 1-3 months of duration.

Because of its numerous advantages, the product has become one of the most popular male enhancement pills and one of the best erection-boosting supplements. It has already racked up more than 1.2 million sales since 2007. Since it is highly beneficial, it is trusted by thousands of men worldwide because it helps improve sexual performance.

According to the makers, once you use the product, you will have bigger and longer-lasting erections, increased sex drive, and very pleasurable orgasms. The best part about VigRX Plus is that an 84-day clinical trial supports its results. It has been featured on popular TV channels and newspapers, including The Wall Street Journal and The New York Times.
How Does VigRX Plus Work?
As you can see in most VigRX Plus reviews, this male enhancement pill features natural aphrodisiacs and libido enhancers that help revitalize your sex life and maintain more excitement during intercourse. Many ingredients are used in the pills, but they are carefully selected to ensure that they regulate your blood pressure level, muscle relaxation, and contraction.

For example, VigRX Plus increases nitric oxide production in your body. Due to the increased supply of nitric oxide, your muscle tissues in the penis get relaxed, allowing smooth and efficient blood flow. In case you don’t know, when you experience increased blood flow in the penis, it offers more massive, stronger, and morale-boosting erections.

The product has many ingredients that promote testosterone production, enhancing your sexual drive. VigRX signals your brain and notifies your central nervous system that you are about to experience warmth and love with your partner.


How to use VigRX Plus?

How to use VigRX Plus?

VigRX Plus manufacturers recommend taking one pill a day for a period of 30 -60 days in order for better efficiency.To get more news about vigrx plus results, you can visit vigrxplus-original.com official website.

Since the internal makeup changes from individual to individual, the rapidity in results also varies; however, the majority of their users achieve desired results in 30 days, tops.

You can continue taking the pill for an extended period of time to enjoy long term benefits.

You can stop using the capsules once you’re satisfied with results; however, continuing for at least 6 months is highly recommended before stopping.

It’s often good to take the pill 20 minutes before breakfast with water or use it 20 minutes before dinner.
Is VigRX Plus safe?
1. Is the product safe for consumption?
Yes, VigRX Plus is 100% safe for consumption due to the fact that this is a herbal product formulated after a lot of studies and based on research findings.
There is a medical advisory committee of doctors and scientists who approve this product.
Millions of customers around the world are currently using this product, and there are thousands of testimonials, reviews, and comments on the internet.
2. Am I being scammed?
VigRX Plus one of the best-rated product in the market.
There are millions of testimonials that claim the worthiness and effectiveness of the product.
3. Will I get the desired results?
Yes, promised results are delivered by VigRX Plus if you tend to use it as recommended by the manufacturer.
All the ingredients are first quality and formulated using a unique combination of 9 potent herbal enhancers.
Unlike therapeutic drugs like Viagra and Cialis, VigRX Plus doesn’t hold any potential ‘active pharmaceutical ingredient’ (API), instead is a combination of multiple herbal products.

First and foremost, all the ingredients are in one way or another used for treating various sexual dysfunctions in the past.

VigRX Plus carefully chose the dosages and made a supplement by combining all of the ingredients.

There are no side effects reported by millions of its users around the globe after using VigRX Plus capsules for an extended period of time.

Apart from a very few who complained about its failed action, there are no major reports suggesting any potential side effect for VigRX Plus.

To be on a safe side any person with a previous history of heart failure, strokes, allergies, kidney failures, under post-anesthetic rest, etc. should consult your doctor before using the pills.


Best Male Enhancement Pills

Best Male Enhancement Pills

Male enhancement pills are natural dietary supplements that can help men with a variety of performance issues in the bedroom. The best male enhancement pills can help you perform at your best with improved libido, enhanced sexual stamina, increased confidence, and better overall sexual performance. These supplements may also help with symptoms of erectile dysfunction without the need for prescription medication.To get more news about vigrx plus, you can visit vigrxplus-original.com official website.

VigRX Plus is a leading male enhancement product that has consistently received #1 ratings from consumers. This supplement contains a unique blend of high-quality natural ingredients, providing several benefits for reproductive health and performance.

Formula Overview
VigRX Plus contains ten ingredients that can build up in your system over time and provide continual benefits for sexual performance. These ingredients target sex drive in a few different ways.

First, VigRX Plus includes a few ingredients that can increase your nitric oxide levels. As a result, you may experience greater blood flow to the corpus cavernosa in the penis, creating a better sexual experience for you and your partner.

Damiana is one of the ingredients that play the biggest role in blood flow. This extract has been a part of ancient medicine since the Mayans first used it as a natural aphrodisiac. However, modern research has shown that damiana may improve oxygen supply and increase blood flow and nerve impulses to the penis.

Ginkgo biloba is another ingredient in the VigRX Plus formula that produces increased blood flow. This Chinese herb can support blood flow throughout the nervous system and to your genitals. This herb also has antioxidant properties to help slow cellular damage.

Additionally, the male enhancement supplement contains natural testosterone boosters, which can increase your testosterone production and give your body access to higher free testosterone levels. Your testosterone levels play a significant role in your sexual health, and keeping them elevated can enhance your sex drive, libido, and performance.

Saw palmetto is one of the primary testosterone boosters in the VigRX Plus formula. This extract can impact your testosterone pathways, increasing your free testosterone production. Researchers are still determining all of the benefits this natural plant extract can produce.

VigRX Plus rounds out its formula with Bioperine, which is a patented form of black pepper extract. This extract can aid your body’s absorption of the formula’s other ingredients, allowing you to gain the most benefits from VigRX Plus.
Key Features
VigRX Plus uses a scientifically engineered formula developed after over ten years of research into male reproductive health. This male enhancement supplement contains optimized ingredients and dosing, allowing you to maximize your benefits from its formula.

You can receive free shipping within the U.S. on select orders and benefit from a 67-day money-back guarantee. This guarantee can allow you to try these male enhancement pills without a monetary commitment. If you’re dissatisfied for any reason, you can return your unopened capsules for a full refund within 67 days of your initial purchase.

The VigRX Plus creators manufacture this male enhancement pill within the U.S., allowing you to feel confident in its safety and quality. The company also uses fresh, high-quality ingredients to ensure a superior product for customers.


Why Do Chinese People Have Slanted Eyes?

Why Do Chinese People Have Slanted Eyes?

Girl in the common bathroom, looking in the mirror, in her hand a needle. Huaihai District, Shanghai, China.To get more news about asian eye slant, you can visit shine news official website.

After a week, there were whiteheads around the sutures, like the tiniest little pearls studding her eyes. She took a sewing needle to them, she'd always had a steady hand, honed by the embroidery her mother had taught her as a child. When she drew blood, she blotted it away impatiently, waiting for it to clear so that she could continue poking into her skin, flicking away each hard bead of concealed oil upended.

It'd been two weeks since she left the People's Liberation Army 455 Hospital. There had been a school-holiday special on double-eyelid surgery: from 3,000 renminbi to 1,999 renminbi, how could she pass on that?

When she moved her eyeballs from side to side, it hurt. She took to swiveling her whole head rather than just her eyes when she had to look at something. She was told that the scarring would take a few months to fade, she was prepared to wait it out. She wasn't told about the possibility of double vision, of the bright lights that would follow.

She was irritated—and hurt—that they ascribed it to vanity. For this wasn't vanity, this was getting ahead in life. Didn't they know that merely having a university degree wasn't the be-all and end-all anymore? The happiest day of my life, her mother said on the day of her convocation, and she was touched but also she had the undercurrent of an urge to take her mother by the shoulders and shake her, to say, Really? Really? Is your life that small, Mother?

Did they know that the chances of employment for a grad with double eyelids and wider eyes are 70 percent higher than those of a grad with single eyelids? That, ceteris paribus, with the same grades and portfolio, the prospective employer will unswervingly choose the one with the double eyelids? Eyes with double eyelids give the overall impression of a person being more energetic. A more energetic person will contribute more productively to the company. There was also the Wuhan study that showed that women could expect to earn 1.5 to 2 percent more for every centimetre of height added, but she would stick to high heels for now.

So when they say, Serves you right for being vain, she wants to say, What do you know. She didn't even ask them to pay for it—and even that wouldn't have been too untoward; she had friends for whom the double-eyelid surgery had been gifted by their parents as natural consequences of completing the gao kao. Weren't you fine before this, they say, with the pair of eyes that heaven above consigned you. When will you get it? she wants to ask them. Why would you ever think that "fine" is enough?

She blinks away the tears, tries to unsee the bright balls of light. The post-surgery ptosis is throbbing, like it sometimes does. She won't hold anything else against him, but it's not fair that she has to live with this droop that was never there before. If she has to, she can live with the rest, the tearing, the temporal scarring, the whiteheads, the bright lights, the double eyelids achieved at the expense of looking perpetually shocked. But the ptosis; can he just please fix the ptosis?
A matter of periocular anatomy. It isn't just the eyes per se we are talking about—there's the flatter nose, the lower-based nasal bridge, the higher amount of preaponeurotic fat in the epicanthic fold. More precisely, the orbital septum fuses to the levator aponeurosis at variable distances below the superior tarsal border, and there is no extension of the capsulopalpebral fascia.

By the by, to term it "Chinese" eyes isn't quite accurate, for the condition isn't unique to the Chinese, but a definitive racial trait of the Mongoloids—though the word is pejorative now, it was utilised in early ethnology and we still use it in academic formality; we mean no harm, but things move so slowly here. We're talking Siberian, North Mongoloid, Central Mongoloid, South Mongoloid, Indonesian, Polynesian, Eskimo, and Amerindian.


CAD Software for 2D Computer-Aided Designs

CAD Software for 2D Computer-Aided Designs

The right CAD system, therefore, is critical to the success of product engineers and designers. But with a myriad of computer-aided design tools available, finding the solution that aligns with your requirements could be a hustle. To get more news about online 2d drafting software, you can visit shine news official website.

3D CAD designs are CPU extensive. Make sure you have a good PC resource to handle it. If you want to have your own powerful custom PC you can take help from PC builders. It will allow you to build a custom personal computer according to your requirements.
1. ActCAD
ActCAD is a 2D & 3D computer-aided drafting tool best suited for engineers, architects, technical consultants, and interior & exterior designers. The software features an advanced Block Library explicitly designed to help architects and interior designers. ActCAD is available in six versions: Standard, Professional, 2020 BIM, Rail Road Sections, Dials & Scales, and Nesting.
2. Tinkercad
Tinkercad is a free and easy-to-use CAD modeling tool ideal for teachers, students, and beginner designers. Its built-in library comprises a wide range of shapes, characters, and numbers, to help you create stunning designs.
3. FreeCAD
FreeCAD is an on-premise 3D modeling CAD system with architectural designs and designing machine tools. This solution is easy to use and enables you to create production-ready drawings.
4. Draftsight
Draftsight is an advanced, feature-rich 2D & 3D CAD system that allows you to create, edit, and view architectural designs with ease. The software offers flexible functions, making it suitable for both beginners as well as professional designers.
5. SketchUp
SketchUp is an advanced CAD modeling with programming, diagramming, and development features for architects, engineers, and designers. It allows you to turn 3D models into documents, thereby eliminating 3D modeling issues.
6. Fusion 360
Fusion 360 is an integrated, cloud-based CAM, CAE, and CAD modeling system ideal for architects and design professionals working in a hybrid environment. This tool offers a consolidated platform for your design teams and enables you to combine your product development processes.
7. Onshape
Onshape is an innovative, cloud-based SaaS design platform that accelerates design and product development. This best CAD software offers all-in-one functionality that integrates CAD, workflow, release management, admin tools, and API.
8. Solidworks
Solidworks is one of the best CAD software available for creating and collaborating 2D drafts, 3D designs, animations, CAD modeling, and more. It integrates robust design tools and drawing capabilities to help you stay ahead of your design requirements.


MWC Shanghai 2023 Wraps Up 10th Anniversary Event

MWC Shanghai 2023 Wraps Up 10th Anniversary Event

After three days of discussion, debate and networking, the GSMA has concluded MWC Shanghai 2023, convening nearly 37,000 attendees from 115 countries and territories, including policymakers and business leaders from the mobile ecosystem and beyond. To get more shanghai news, you can visit citynewsservice.cn official website.

“MWC Shanghai 2023 has been truly inspirational and we are so grateful for the close collaboration and support from Cyberspace Administration of China; Ministry of Industry and Information Technology; Shanghai Municipal People’s Government; China Mobile, China Telecom, China Unicom and China Broadnet, our partners, exhibitors and sponsors. We sincerely thank them for helping us deliver MWC Shanghai 2023. It is their level of energy and support that ensured we were able to deliver a world-class event that exceeded our expectations,” said John Hoffman, CEO of GSMA Ltd.
Upcoming events

MWC Shanghai is part of the MWC series of events, held by the GSMA alongside the M360 series of events. Join us as we continue our journey to unlock the full power of connectivity at MWC Las Vegas, which is scheduled for 26-28 September 2023 followed by MWC Kigali, 17-19 October 2023. The M360 series will continue with M360 APAC in Seoul between 7-8 September, followed by M360 MENA in Riyadh from 6-7 November.

Next year’s MWC Shanghai 2024 will take place 26-28 June 2024. News and updates from MWC Shanghai, as well as official event photography, are available on the event website press zone.

The GSMA is a global organisation unifying the mobile ecosystem to discover, develop and deliver innovation foundational to positive business environments and societal change. Our vision is to unlock the full power of connectivity so that people, industry, and society thrive. Representing mobile operators and organisations across the mobile ecosystem and adjacent industries, the GSMA delivers for its members across three broad pillars: Connectivity for Good, Industry Services and Solutions, and Outreach. This activity includes advancing policy, tackling today’s biggest societal challenges, underpinning the technology and interoperability that make mobile work, and providing the world’s largest platform to convene the mobile ecosystem at the MWC and M360 series of events.


Viagra Performs Not Only in Bed, But in the Heart

Viagra Performs Not Only in Bed, But in the Heart

Older men like Playboy’s Hugh Hefner and actor Michael Douglas have sung the praises of Viagra, but now scientists say the erectile dysfunction pill is not only good for your sex life — it’s good for your heart.To get more news about vigrx oil reviews, you can visit vigrxplus-original.com official website.

In the bedroom, Viagra allows greater blood flow to the penis. But in the heart, the “little blue pill” can prevent heart muscle thickening and early-stage heart failure, according to research published today in the open access journal BMC Medicine.

"Large clinical trials are now urgently needed to build on these encouraging findings,” said lead author Dr. Andrea M. Isidori, associate professor of endocrinology at Sapienza University of Rome.

Dosages used for heart ailments are lower than those used for erectile dysfunction, and patients in the study showed few side effects. “Surprisingly, in over 1600 treated subjects, no increased risk of visual disturbance, photosensitivity and ‘blue haze,’ was observed,” he told NBC News.The active ingredient in Viagra is sildenafil citrate, which is a phosphodiesterase type 5 inhibitor (PDE5i). The inhibitor blocks the enzyme PDE5, which prevents relaxation of smooth muscle tissue.

Researchers analyzed randomized trials that had been published between January 2004 and May 2014, choosing 24 involving mixed populations of patients who were treated with PDE5i or a placebo. PDE5i was given to men who had cardiovascular disorders, but who did not necessarily suffer from sexual impotence, according to Isidori.

The study found that the inhibitor prevented the heart from changing shape in patients suffering from left ventricular hypertrophy, a condition that causes thickening and enlargement of the heart muscle. The drug also improved functioning of the heart in patients with a variety of cardiac conditions, with no effect on blood pressure.

In fact, researchers found that the drug improved efficiency when the heart pumped blood into vessels, along with relaxation between beats. “Very few drugs used in cardiology can actually affect these parameters. For this reason their implications in the treatment and prevention of heart failure are huge.”“I am not surprised and it’s good news,” said Dr. Robert A. Kloner, professor of medicine in the cardiovascular division at the Keck School of Medicine at USC in California. “We can always use a new drug for heart failure."

Kloner co-authored the book, “Viagra: How the Miracle Drug Happened & What It Can Do for You.” He said this is not the first time, scientists have looked to Viagra for potential heart benefits.

In 1989, British scientists tested sildenafil citrate as a medication to treat high blood pressure and angina. By the 1990s in early trials of the drug, researchers noticed an interesting side effect — an increase in erections.

In 1996, the pharmaceutical company Pfizer patented it as Viagra, and in just two years, doctors had ordered more than 40,000 prescriptions of the new wonder drug. “When the drug first came out there was a big scare — is this going to kill people?” said Dr. Robb D. Kociol, director of the heart failure program at the CardioVascular Institute at Beth Israel Deaconess Medical Center in Boston.


The drugs that protect people who have unprotected sex

The drugs that protect people who have unprotected sex

For decades sexual health workers have concentrated on the message of always using a condom as the main tactic against the spread of HIV and other sexually transmitted infections.To get more news about buy vigrx oil, you can visit vigrxplus-original.com official website.

But certain risky behaviours are on the rise. Illegal drugs like MDMA and speed have long been used on the gay club scene. But now "chemsex" is a growing problem - parties in private homes centred on communal drug taking and sex.

The likes of mephedrone, crystal meth and GHB/GBL (or "G" for short) can increase libido and dramatically decrease inhibition and the desire to sleep.

It's impossible to know how many men have become infected with HIV while using chems, but condom-less sex is normal for many men on the chem scene. In a study published by the London School of Hygiene and Tropical Medicine, a third of men surveyed described incidents of unintended unprotected sex while under the influence of chemsex drugs.

Simultaneously, HIV infection rates are rising. One in every eight gay men in London is HIV positive.

Kiran is one of them. "Once you try a powerful drug like crystal meth, and if that's linked to sex, that's the kind of sex you're going to want. Vanilla sex just doesn't compare. Your boundaries shift."

He began using chems after a break up with his long-term boyfriend. "Sometimes I was safe but when I didn't use a condom I would see it as a cheeky risk. When I was diagnosed as HIV positive I felt there was no point in holding back at all. I began injecting crystal meth and had absolutely no boundaries. I would try anything when I was high."

A new type of drug treatment - Pre-Exposure Prophylaxis (PrEP) - could offer protection against HIV infection. People are given a combination of anti-HIV drugs tenofovir and emtricitabine - currently being sold under the trade name Truvada - before they have unprotected sex. The drug is taken as a single pill and halts the replication of the virus, stopping infection.
Dr Sheena McCormack from University College London is leading the study. "To take part gay men had to identify that they had had condom-less anal sex in the three months prior to the study and recognise that this was likely to happen again in the near future."

Just over 40% of the men on the study had used chems in the three months prior to joining the study, McCormack says. "We found no HIV infections amongst men who took Truvada during periods of risk. It is extremely effective but it does rely on human behaviour. You do have to take the pill."

The World Health Organization has recognised that PrEP could dramatically cut HIV infection rates but some critics suggest the drug could encourage condom-less sex. Taking PrEP does not offer protection against infections such as gonorrhoea, syphilis or hepatitis. So could these infections increase if the drug is made widely available?

PrEP should be used in combination with condoms, says McCormack. "There was a slight reduction is condom use among men on the trial who took Truvada but I don't think it's a problem what people do in the bedroom unless it generates an increase in infections such as syphilis, gonorrhoea and hepatitis. We didn't see that in the study. There was no increase. Most people say they have not abandoned their previous strategies."


Top 5 Natural Male Performance Enhancers of 2023

Top 5 Natural Male Performance Enhancers of 2023

Male enhancement pills are natural dietary supplements that can help men with a variety of performance issues in the bedroom. The best male enhancement pills can help you perform at your best with improved libido, enhanced sexual stamina, increased confidence, and better overall sexual performance. These supplements may also help with symptoms of erectile dysfunction without the need for prescription medication.To get more news about vigrx oil review, you can visit vigrxplus-original.com official website.

But with so many male enhancement pills sold in stores and online to choose from, picking the right sexual pills for men can be intimidating. To help you decide, we’ve reviewed the top male enhancement pills on the market. Each natural male enhancer below was rated on a variety of factors including ingredients, benefits, price, and reviews.
Formula Overview
Erectin contains a unique polyherbal blend of berries, barks, leaves, roots, and herbs. These ingredients can all treat erectile dysfunction differently.

Muira puama bark extract is one of the most powerful ingredients in the Erectin formula. This ingredient, commonly known as “Potency Wood,” can enhance several aspects of sexual performance. You may see stronger libido, better sexual stamina, and more intense orgasms while taking this extract. It can also boost energy and reduce stress.

The supplement also contains Chinese hawthorn berry extract, which is full of antioxidants to help reduce cell damage. It may also have vasodilating effects, meaning that it could open the blood vessels to allow more blood to flow to your genitals during sex. Hawthorn berry may also promote healthy blood pressure.

Cuscuta chinensis is another essential ingredient in the Erectin formula. This plant extract is a powerful aphrodisiac that contains phytochemicals to enhance sexual function and libido.

Erectin also includes Bioperine black pepper extract, which can encourage nutritional uptake. Combining this extract with the formula’s other ingredients can enhance your absorption of their nutrients.
Formula Overview
ProSolution Plus contains a blend of all-natural extracts, nutrients, and minerals to promote sexual prowess.

First, this formula includes Tribulus terrestris, a traditional Chinese herb. This herb acts as a natural aphrodisiac, stimulating feelings of libido and sexual satisfaction in both men and women. Additionally, Tribulus terrestris may help relax the corpora cavernosa in the penis, helping with symptoms of erectile dysfunction.

Sometimes, the cause behind premature ejaculation is simply stress. ProSolution Plus also contains Asparagus adscendens to aid feelings of stress that may inhibit sexual performance. This ingredient can inhibit proinflammatory cytokines, providing natural stress and inflammation relief.
Formula Overview
VigRX Plus contains ten ingredients that can build up in your system over time and provide continual benefits for sexual performance. These ingredients target sex drive in a few different ways.

First, VigRX Plus includes a few ingredients that can increase your nitric oxide levels. As a result, you may experience greater blood flow to the corpus cavernosa in the penis, creating a better sexual experience for you and your partner.

Damiana is one of the ingredients that play the biggest role in blood flow. This extract has been a part of ancient medicine since the Mayans first used it as a natural aphrodisiac. However, modern research has shown that damiana may improve oxygen supply and increase blood flow and nerve impulses to the penis.

Ginkgo biloba is another ingredient in the VigRX Plus formula that produces increased blood flow. This Chinese herb can support blood flow throughout the nervous system and to your genitals. This herb also has antioxidant properties to help slow cellular damage.


Choosing the Right Pill to Treat ED

Choosing the Right Pill to Treat ED

The most common sexual dysfunctions in men include lack of interest, premature ejaculation and erectile dysfunction. The latter affects 52% of men between the ages of 40 and 70, including mild, moderate and complete forms of ED.To get more news about vigrx plus price, you can visit vigrxplus-original.com official website.

Organic or physical causes for sexual dysfunction in men include vascular, hormonal and neurologic factors. Concerning vascular causes, the risk factors for atherosclerosis (including smoking, high blood pressure, diabetes (diabetics do not respond well to pills like sildenafil (Viagra)) and high cholesterol are ALSO risk factors for erectile dysfunction. Since a straddle injury or use of a narrow saddle can obstruct and impair arteries to the penis, bicycle riding is also considered a risk factor for erectile dysfunction.

Little attention has been paid to endocrine factors. Testosterone modulates desire, arousal and orgasmic function. Concerning the orgasmic response, testosterone modulates the integrity of genital sensory receptors. Concerning the arousal response, decreased testosterone blood levels can influence the efficacy of sildenafil (Viagra). If the sildenafil response is not reliably improving erection, the physician should first check if the patient is taking the pill correctly. The physician should also check the patient’s testosterone level. One investigator in Italy gave testosterone to patients with low testosterone who did not respond to sildenafil (Viagra). When daily testosterone was given, subsequent sildenafil (Viagra) use resulted in IIEF (the International Index of Erectile Function questionnaire used to determine erectile function) scores improving significantly.

Other risk factors for erectile dysfunction include neurologic problems (multiple sclerosis, stroke), depression and medications for treating diabetes, hypertension, heart disease and depression.

There are many oral therapies for erectile dysfunction, but the only approved medication in the US is the PDE 5 enzyme inhibitor sildenafil (Viagra). Unapproved therapies, some of which are available in the US and some elsewhere, some of which have data to prove efficacy and some not, include tadalafil (Cialis), vardenafil (Levitra), yohimbine, phentolamine, trazodone, apomorphine and neutraceuticals. PDE5 inhibitors act to relax penile erectile tissues with sexual stimulation thus enhancing your ability to get an erection. Sildenafil (Viagra) is effective for all sorts of erectile dysfunction in 69% of people. Why is there a need for another pill? In some cases the erection is not hard enough, sometimes sildenafil (Viagra) just doesn’t work.

Structurally vardenafil (Levitra) is similar to sildenafil, while tadalafil (Cialis) is very different. Vardenafil (Levitra) is almost 10 times more biochemically potent than sildenafil, therefore a lower dose is needed to facilitate the penile erection, potentially resulting in less side effects. Selectivity is the ability of the drug to attach to the specific enzyme PDE 5 found in penile tissues. Vardenafil (Levitra) is more selective than sildenafil and tadalafil (Cialis) to PDE5, which again means a lower dose is needed with potentially less side effects. Tadalafil is very specific for PDE5 and is also very specific for the enzyme PDE11. Unfortunately, we don’t know much about PDE11, which is found in the heart, in the pituitary gland in the brain and in the testicles. Pharmacokinetics, half-life, is how long the medication stay s in the blood. Sildenafil (Viagra) has a half-life of 4 hours and vardenafil (Levitra) has a half-life of 4-6 hours while tadalafil (Cialis) has a half-life of 17.5 hours. This means that vardenafil (Levitra) should act longer than sildenafil (Viagra) but the clinical significance is not known. Tadalafil (Cialis) has the longest half-life and allows you to take the medication and not relate the sexual activity to the immediate use of the medication. The drawback is if you need nitrates after using tadalafil (Cialis), this medication lasts a long time in your blood stream and may place you at a higher risk. Younger people might do well treated with tadalafil, (Cialis) while older people with other health issues might be better off using sildenafil (Viagra) or vardenafil (Levitra) but more data are needed. The side effects of vardenafil (Levitra) are potentially less than sildenafil (Viagra), but more data are needed. In a recent study on men with erectile dysfunction and diabetes, vardenafil (Levitra) improved their erectile dysfunction. Tadalafil (Cialis) is as effective as sildenafil (Viagra), and vardenafil (Levitra) with similar side effects except for back pain that occurs occasionally with tadalafil, probably because of the long half-life.

Many people stop taking drugs because they are experiencing side effects, they no longer have a partner, or they are worried about safety. Sexual activity is not a major contributor to the risk of a heart attack. Sexual activity, with or without sildenafil (Viagra) increases the chance of an MI during sexual activity by only 0.1%. If pills fail, there are vacuum devices, Muse, injections, bypass surgery and implants.



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