wisepowder's Blog

Differential effects of heat-not-burn and conventional cigarettes

We compared the effects of HNBC to those of tobacco cigarette (TCig), on arterial stiffness, oxidative stress, and platelet activation, acutely and after 1 month of switching to HNBC, as well as on endothelial, myocardial, and coronary function after 1 month of switching to HNBC. In the acute study, 50 smokers were randomised into smoking a single Tcig or an HNBC and after 60 minutes were crossed over to the alternate smoking (HNBC or Tcig). For the chronic phase, 75 smokers were examined. Of those, 50 were switched to HNBC and 25 continued Tcig for 1 month. Pulse wave velocity (PWV) and biomarkers [malondialdehyde (MDA), protein carbonyls (PC), and thromboxane B2 (TXB2)] were assessed in the acute and chronic study. Myocardial deformation [global longitundinal strain (GLS), myocardial work index (GWI) and wasted myocardial work (GWW)], coronary flow reserve (CFR) by echocardiography, total arterial compliance (TAC), and flow-mediated dilation (FMD) were additionally assessed in the chronic study.To get more news about HNB, you can visit hitaste.net official website.

The tobacco industry’s most recent response to the documented harms of cigarette smoking was to launch new heat-not-burn (HNB) tobacco cigarettes.¹ Philip Morris International (PMI) created IQOS (I-Quit-Ordinary-Smoking): disposable tobacco sticks soaked in propylene glycol, which are inserted in a holder in the HNB cigarette. The tobacco is heated with an electric blade at 350°C. The cigarettes are marketed by PMI as a “revolutionary technology that heats tobacco without burning it, giving you the true taste of tobacco, with no smoke, no ash and less smell.”² In many countries, laws that protect people from passive smoke only apply to smoked tobacco products. Philip Morris International claims that IQOS releases no smoke because the tobacco does not combust and the tobacco leaves are only heated not burned. However, there can be smoke without fire. The harmful components of tobacco cigarette smoke are products of incomplete combustion (pyrolysis) and the degradation of tobacco cigarettes through heat (thermogenic degradation). Complete combustion occurs at a high temperature (>1300°C), higher than the heat generated by smoking a tobacco cigarette (<800°C). Typical markers of pyrolysis and thermogenic degradation of tobacco cigarettes are acetaldehyde, an irritant carcinogenic volatile organic compound, benzo[a]pyrene, a carcinogenic polycyclic aromatic hydrocarbon, and carbon monoxide.


WoW Economy to Allow Players to Buy Game Time with In-Game Gold

Diablo 3‘s auction house, Blizzard’s first attempt at a real money for in-game items system, was a pretty dramatic failure, but that isn’t stopping them from giving it one more go.To get more news about safe wow gold, you can visit lootwowgold official website.

The company has announced that World of Warcraft will be getting a “token” system that will allow players to exchange in-game gold for game time, or on the flip side, buy gold using real money.

How does this system work?
Basically, players can now purchase a “Wow Token” through the in-game shop using real cash. If used, this item will add 30 days of game time to their account.

Instead of using it though, you can put a Wow Token on the Auction House at the current market price. Players interested in purchasing game time can then buy your token, at the previously set market price, using gold. The Auction House will be the only way to trade and sell Tokens.After the D3 Auction House fiasco, I’ll agree, but I assume that Blizzard learned some important lessons there that they’re putting to use here.

While the idea of letting players use real money to effect the in-game economy sounds pretty iffy, there is some precedent. Games like EVE Online and Wildstar have similar systems in place, and nothing has caught on fire over in their communities quite yet.

From a gameplay standpoint, this will also allow players who spend a lot of time in WoW, and have excess gold lying around, to get a discounted (or even a complimentary) subscription to the game. Meanwhile, those who need a leg up now have a legit way to buy gold with money, instead of going through a dubious gold farming service.More than likely (among other things of course). In their announcement, Blizzard flat out states that their goal is to provide “a secure, legitimate way to acquire gold that doesn’t involve the use of unauthorized third-party gold-selling services—one of the primary sources of account compromises.”

I’m sure gold farmers, and all of the scam risks that they entail, have been a major thorn in Blizzard’s side for years. This could be a pretty straightforward solution to cutting them out of the loop.


The WoW Classic beta lets you play from level one to 30 starting tomorrow

You can opt in for the beta at the official site. When the beta launches on May 15, players who’ve gotten in will be able to play all the way from from level one to 30. WoW game director Ion Hazzikostas tells us that the beta will be “uncharacteristically small compared to our expansions,” in part to ensure that the focus is on the proper launch this August.To get more news about WoW Gold TBC, you can visit lootwowgold official website.

The content of the beta may expand or shift over time as the developers look for feedback on specific points, and we may similarly see more “focused tests on specific pieces of content as needed.”

In addition to the beta, stress tests will also begin this month, and will continue to run through July. You can opt in for those at the same link above.WoW Classic officially launches on August 27. It aims to be the WoW you remember from back in the day – just with the added benefit of modern infrastructure and proper Battle.net integration.
Blizzard now lets World of Warcraft players trade in their gold for WoW tokens, and then trade those in for Battle.net moolah—letting you make purchases in any Blizzard game.You can buy a token in the game and then sell it to another player for gold. But once its sold the token is soulbound. So the buyer can only exchange the Token for 30 days of game time or add it to their Battle.net balance.

Thanks to the update, Token valuations are on the rise. The price has nearly doubled in the last 24 hours.WoW's system is similar to the way EVE Online's PLEX works: it can be bought and sold from the developers and has a fluctuating market value. Blizzard originally developed the token to combat gold selling.


China’s Travel Restrictions due to COVID-19

China will ease entry restrictions for foreigners inoculated with Covid-19 vaccines made in China, according to some Chinese embassies (See here). The said visa facilitation applies only to applicants who have been inoculated with COVID-19 vaccines produced in China (either having received two doses of Chinese-made vaccines with the stipulated gap in between, or having received a single-dose Chinese-made vaccine at least 14 days prior to the application) and obtained the vaccination certificate. A proof of a negative COVID-19 nucleic acid test result and the Health and Travel Record Declaration Form for Visa Application are no longer required. The new rules in some places have taken effect on March 15, 2021. In addition, according to China’s foreign minister Wang Yi, the country plans to issue international electronic health certificates and implement mutual recognition of other countries’ nucleic acid testing and inoculation, to allow “a healthy, safe, and regulated new order for cross-border exchanges of people.”To get more news about China travel advice, you can visit shine news official website.
China Briefing offers a few observations on the latest changes in travel / entry into China for foreign nationals: China to Allow Entry of Foreigners with Valid Residence Permits.
According to a statement released by the Ministry of Foreign Affairs and the National Immigration Administration on Wednesday, foreign nationals holding valid Chinese residence permits for work, personal matters, and reunion can enter China without applying for new visas – effective from 0 am, September 28, 2020. If these 3 categories of residence permits as held by foreign nationals have expired (in the time since the travel ban was imposed on March 28, 2020) – the holders may apply for relevant visas by presenting the expired residence permits and relevant material to the Chinese embassies or consulates on the condition that the purpose of the holder’s visit to China remains unchanged (see here). All other measures in the March 26 Announcement by the Ministry of Foreign Affairs and the National Immigration Administration on the Temporary Suspension of Entry by Foreign Nationals Holding Valid Chinese Visas or Residence Permits (see here) will continue to be implemented.
Chinese state media announced that starting September 3, the country is resuming direct flights from eight countries, including Thailand, Cambodia, Pakistan, Greece, Denmark, Sweden, and Canada.
Latest update: As of August 27, China has opened its borders to 36 European countries and 13 Asian countries (see the “International travel restrictions” section for more details).
This article provides information on the latest travel policies in China – implemented temporarily due to COVID-19 – to help business travelers understand the current situation and develop feasible travel plans.
We address some frequently asked questions with regards to foreigners managing their China residence and work permits when stuck abroad due to the travel ban in our article here and share three successful cases of foreigners’ special visa application in our article here.
COVID-19 is now a global pandemic, and in a bid to prevent a second wave of the outbreak at home, China has not given up on drastic measures to contain infections or possibility of reinfection. However, with the epidemic in domestic areas basically under control, the country has recently begun relaxing travel restrictions.

Since March 28, the country’s borders have been closed to almost all foreigners. This looks to be slowly changing. On August 10, China announced that foreign nationals from 36 European countries who hold valid residence permits, including work permits or permits for family reunion and personal matters, can apply for visas for free and directly at any Chinese embassy or consulate to enter China. In addition to these European countries, according to official sources, foreign nationals with valid residence permits (employment, personal affairs, and reunion) from a list of 13 Asian countries are also allowed to apply for visas at local Chinese embassy or consulate.

Since March 29, the Civil Aviation Administration of China (CAAC) has implemented the so-called five-one policy to cap international flights and reducing the number of international flights on China bound routes. This was relaxed from June 4, when the CAAC started allowing more international flights into China.

While the virus hasn’t fully disappeared, and sporadic outbreaks reported in individual cities – China is still adopting a strict isolate-and-tracking strategy in high-risk areas. (At the time of this article update, most of the country has been classified as low-risk.)


Dominar el arte del comercio de acciones de precio en el mercado Forex

Convertirse en un trader profesional en el mercado Forex es una tarea muy desafiante. Los traders novatos a menudo piensan que los traders profesionales tienen acceso a información privilegiada y, por lo tanto, pueden obtener ganancias consistentes. Pero si investiga sobre el operador exitoso, comprenderá que están ganando dinero con solo usar una estrategia comercial simple.To get more news about mercado forex, you can visit wikifx.com official website.

  La naturaleza del mercado Forex es dinámica y nadie puede predecir el movimiento del precio del activo financiero con una precisión del 100%. Incluso el poderoso presidente de los Estados Unidos no puede manipular el precio de un determinado activo durante un período de tiempo prolongado. Solo piense con su lógica y comprenderá que no es posible cambiar el desempeño de la economía de un determinado país con pocas declaraciones simples.

  Los traders profesionales de forex prefieren el trading de forex porque saben que este mercado está libre de manipulaciones. No tiene que aprender todo de entrada para convertirse en un comerciante exitoso. Simplemente aprenda lo básico de las tres formas principales de análisis de mercado y comprenderá la manera perfecta de operar en el mercado. Algunos de ustedes pueden pensar que la estrategia comercial basada en indicadores es la mejor manera de ganar dinero, pero en realidad, los indicadores no son más que una pérdida de dinero. Intente dominar el sistema de negociación de acciones de precio para que pueda ejecutar operaciones de calidad con un stop loss ajustado.
La negociación de la acción del precio no es más que utilizar las diferentes formaciones del patrón de velas japonesas para encontrar las posibles configuraciones comerciales. Comprender las diferentes formaciones del patrón de velas japonesas en la etapa inicial será un poco difícil, pero si se enfoca en los factores psicológicos detrás de las formaciones de cada vela, podrá obtener una ganancia decente. Hoy le daremos algunos pasos sencillos que le ayudarán a convertirse en un trader profesional de la acción del precio.

Analizar los datos del Timeframe (TF) más alto
  
  Al ser un operador nuevo, es muy normal que opere en el mercado en el período de tiempo más bajo. Los traders novatos prefieren datos de marco de tiempo más bajo, ya que les permite ejecutar más operaciones. El sobreoperar no es más que aumentar su exposición al riesgo. Incluso después de usar la señal de confirmación de la acción del precio, será realmente difícil encontrar configuraciones comerciales de calidad en el marco de tiempo más bajo. Para ser precisos, debe convertirse en un operador de posición o de largo plazo para utilizar la señal de confirmación de la acción del precio.

  Aunque la estrategia de negociación de la acción del precio tiende a funcionar mejor en un período de tiempo más alto, esto no significa que no podrá obtener ganancias al ejecutar una operación en el período de tiempo más bajo. Los revendedores profesionales utilizan una técnica simple llamada análisis de marco de tiempo múltiple para filtrar el patrón de velas falsas en el mercado. En la etapa inicial, realizar el análisis de múltiples marcos de tiempo será extremadamente difícil, pero durante el período de tiempo, puede dominar estas habilidades fácilmente.
  Aquellos que buscan operar en el marco de tiempo más bajo utilizando la señal de acción del precio nunca deben operar con noticias de alto impacto. Durante el evento de un comunicado de prensa de alto impacto, el mercado de divisas se vuelve extremadamente volátil y un pequeño error resulta en una gran pérdida. Si tiene la intención de salvarse de tales problemas, es muy imperativo que se mantenga al margen durante noticias de tan alto impacto.
  La respuesta simple es SI. De hecho, el comercio de noticias es una de las formas más fáciles de captar los grandes movimientos del mercado, pero requiere años de experiencia. Nunca ejecute ninguna operación antes del comunicado de prensa. Una vez que se publiquen los nuevos datos, evalúe sus datos técnicos con los datos fundamentales. Si las cosas van a su favor, ejecute la operación según la señal de confirmación de la acción del precio en el marco de tiempo inferior. Pero asegúrese de no arriesgar más del 2% del saldo de su cuenta mientras intercambia las noticias.


ТЕХНИЧЕСКИЙ АНАЛИЗ РЫНКА К КОНЦУ НЕДЕЛИ

Пара EUR/USD остается под давлением растущего доллара. Американская валюта укрепляется на фоне роста доходности облигаций. На фоне таких событий, как увеличение доходности госбондов и увеличение спроса на доллар из-за краха хедж-фонда Archegos Capital, котировки EUR/USD достигли уровня поддержки 1.1712 и по некоторым анализам следующей целью может стать отметка 1.1616.To get more news about анализ, you can visit wikifx.com official website.

  Однако к концу дня нисходящая тенденция пары EUR/USD развернулась на краткосрочную восходящую коррекцию к ближайшему уровню сопротивления 1.1760.Пара EUR/JPY выросла на фоне стремительного ослабления иены против доллара США.

  В результате котировки EUR/JPY приблизились к уровню сопротивления бокового диапазона 128.97–129.97.  Пара USD/JPY является одной из самых торгуемых валютных пар (уступая только EUR / USD). На данный момент восходящая тенденция развернулась на краткосрочную нисходящую коррекцию, закрепившись ниже уровня 110.70.

  Для валютной пары AUD/USD восходящая коррекция продолжительное время не может пробиться выше уровней сопротивления 0.7625 – 0.7645, образуя ложные пробои.

Валютная пара USD/RUB - среднесрочная нисходящая коррекция пробилась ниже сильного, исторического уровня поддержки 75.80, образовав новый нисходящий канал.

  По данным Московской биржи минимальный курс доллара составил 75.22 руб., максимальный – 76.01руб, а последняя сделка была совершена по курсу 75,53 руб. за доллар США.  На текущей неделе нисходящая коррекция остановилась на уровне поддержки 57501, образовав ложные отскоки вверх.


Isang Account Killer Lubos na mas Malakas Kaysa sa Mabigat na Posisyon

Mga Estratehiya sa Pagte-trade sa WikiFX (30 Marso 2021) - Traders who refuse to stop loss or close the position timely when suffering losses are holding their orders floating. They take a chance on the market but forget that it is the sharpest account killer even more lethal than a heavy position.To get more news about estratehiya, you can visit wikifx.com official website.

  Some people are not willing to acknowledge mistakes. They hold positions floating until making a profit again, but often end up with a terrible loss of hundred points.

  There are market changes as high as one to two thousand points every year, thus participants are used to trading on a few hundred points of volatility. In other words, traders always have a few opportunities to see position floating in a year, which, however, will not lead to good performance.

  First of all, they might only trade forex for a short period without experiencing any significant market changes. If they continue such an operation, chances are their accounts will be blown up within a half year.

  Secondly, they could hardly make a profit even if their positions drift back because they will have missed the opportunity to double the account value.

  Besides, as long as you have a loss position floating, you are easy to show negative feelings about the market, which will cause worse mistakes and heavier losses!

  On the contrary, if you timely close the loss position and trade on opportunities, earning money is fully possible. Keep this in mind: let your position floating will ruin everything! To trade flexibly is the first rule that overrides all others, and a timely stop loss could serve as the security belt of your account!


Biden Infrastructure Plan May Direct XAG/USD Higher

Silver investors may get a big driver this week in the form of US President Bidens infrastructure-focused stimulus announcement. Mr. Biden will outline his plan in Pittsburgh on Wednesday, according to White House administration officials. To avoid GOP resistance, the infrastructure plan will reportedly be separate from other priority legislation such as healthcare and child care funding, according to Biden aides cited in the Wall Street Journal.To get more news about Silver, you can visit wikifx.com official website.

  Silver may benefit from the announcement, with many looking at the precious metal – which also has applications in industry – to be an inflation hedge. However, market-based inflation expectations implied in breakeven rates have continued to move higher even as silver veered off downward recently. Divergence may continue until a realized inflationary pickup is reflected in CPI and PCE figures.

  Regardless, the plan, which will focus on roads, bridges, airports, and green energy initiatives, will most likely be larger in size than any similar initiative before it. Many are estimating the size of the package to be in the trillions, likely near $3 trillion to start, although negotiations with Republicans – who worry about tax increases to fund the measures – may see the final total revised lower.

  That said, inflation expectations are likely to rise further following this week‘s announcement. Breakeven rates, which measure price growth expectations by tracking the difference between yields on nominal and inflation-adjusted Treasury bonds (TIPS), have been on the rise since crashing last March. Since Mr. Biden took office however, the 5-year breakeven has accelerated past the 10-year breakeven rate, a reflection of the new administration’s willingness to quickly spend more to stimulate the economy.

  Overall, the pickup in inflation expectations may bode well for silver prices. An argument can be made that silver is merely in a phase of consolidation after a large run in 2020, and the upcoming green-focused infrastructure bill may be the catalyst needed to propel the metal to new heights. That may very well be the case, although any proposal will first need to test the waters in Congress. Given these points, silver investors will want to watch the Biden administration closely this week, particularly Wednesdays announcement from the President himself.
Silver is down nearly 6% on the month, and XAG/USD is now trading directly above its 200-day Simple Moving Average (SMA). So far, this key barrier appears to be providing a level of support, with prices remaining above the psychologically important 25 handle, which also coincides with the 78.6% Fibonacci retracement of the December to February move.

  A break below the 200-day SMA would likely see additional selling pressure mount, perhaps with a move down to the 22.597 area that supported swings lower during the September and November selloffs last year. XAG/USDs MACD oscillator is skewed to the bearish side as it trends lower. Alternatively, if prices continue to hold above support, a retest of trendline support from the March 2020 swing low remains on the cards to reestablish a bullish technical posture.


Comment faire face à des brokers douteux ?

Il est déjà difficile de gagner des bénéfices en trandant le Forex, et cela deviendra plus difficile lorsque vous faites face à des brokers douteux. Vous trouverez ci-après des conseils concernant les brokers :To get more news about broker, you can visit wikifx.com official website.

  1. Si vous voyez des commentaires négatifs concernant un broker, il vous faudra savoir : Parfois, les pertes sont à l‘origine des traders eux-mêmes, qui sont plutôt les débutants. Une fois qu’ils auront subi des pertes, ils mettront en doute leurs brokers, au lieu de leur propre aptitude.

  De temps en temps, les pertes peuvent être causées par les brokers : Certaines plates-formes ont délibérément corrigé les cotations afin de pousser les commandes de leurs clients vers les arrêts de pertes. Ce type d‘arnaques sont assez rares, mais il faut bien savoir que les brokers veulent gagner des frais de commission en augmentant leur volume de transactions, et c’est pour cela qu‘il n’existe pas un jeu à somme nulle. Par conséquent, il faut évaluer correctement lindustrie du Forex et faire attention aux identifications des brokers.

  2. Si le broker n‘était plus joignable ou qu’il commençait à tourner autour du pot, cela pourrait signifier qu'il ne prenne plus en considération les intérêts de ses clients.

  3. Protégez-vous en appliquant les critères comme suit :

  1) Recherchez les commentaires sur le broker et ses réactions, pour bien répérer la vérité.

  2) Si vous constatez une plainte, il vous vaudra mieux vous renseigner suffisamment auprès le plaignant.

  3) Lors de l‘ouverture de compte, lisez attentivement les contenus connexes, afin d’éviter les mauvaises conséquences sur vos retraits.

  4) Si vous étiez satisfait d'un certain broker, vous pourriez déponser un petit montant de fonds pour faire un test.

  La taille d‘un broker n’a pas de relation avec son niveau de gestion des risques. En cas de litige, gardez toutes les évidences et ayez recours au régulateur.

  L'APP WikiFX, outil pratique de renseignement sur les brokers mondiaux utilisé par les traders intelligents ! Cliquez ici pour télécharger : https://cutt.ly/WikiFXfr (Android) /https://bit.ly/wikifxFiOS (iOS).


【初心者向け】仮想通貨のステーキングとは?

仮想通貨コインを直接売買する事とは別に保有するだけで、利益が得れると言われているステーキングと呼ばれるものを目にします。今回はステーキングとはどのようなものなのか、なぜコインを保有するだけで利益が出るのかを調べました。To get more news about 投資初心者, you can visit wikifx.com official website.

  イーサリアム、Bitcoinを含む仮想通貨/暗号通貨の情報はWikiBitで扱っています!今後も引き続き仮想通貨やビットコイン等の情報をチェックしてみてください!

ステーキングとはビットコインにおけるマイニングに相当するプロセスで、保有しているだけで報酬を得ることができる仕組みで、本日はそのステーキングの仕組みを簡単にご紹介します。



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